Premna integrifolia -Munnai
• Antibacterial: The alcoholic extract of the root bark showed good antibacterial activity against gram-positive organisms in a preliminary screening.
• Immunomodulatory Activity: The roots of both plants of C. phlomidis and Premna integrifolia are incorporated in many valued Ayurvedic formulations. In a study evaluating the roots for immunomodulatory potential, both roots showed immunoprophylactic effect with C phlomidis showing higher response to specific immune activity. In no specific immune activity, both roots showed equal response.
• The effect of Premna integrifolia Linn. (Verbenaceae) on blood glucose in streptozotocin induced type 1 and type 2 diabetic rats.
• Hypoglycemic activity: In a study of 30 hypoglycemic plants from indigenous folk medicines, Preman integrifolia wsas one of 24 samples that showed significant blood glucose lowering activity.
• Premnazole / Anti-Inflammatory Activity: Premnazole, an isoxazole alkaloid from Premna integrifolia and Gmelina arborea exhibited signnificant anti-inflammatory activity in rats, comparable to that of phenylbutazone.
• Cardiac Stimulant Activity: PS contains alkaloids and iridoid glycoside. Study suggests that the ethanol extract produced a cardiotonic effect and the aqueous extract produced a ß-adrenergic effect.
• Hepatoprotective / Cytotoxic Activity: Study showed the alcoholic extract with significant hepatoprotective activity evidenced by decrease of serum enzymes, bilirubin and lipid peroxidation, comparable to drug silymarin. It also exhibited significant in-vitro cytotoxic activity. Results showed the alcoholic extract not only as an effective hepatoprotective agent, but with also significant antitumor activity.
• Antiparasitic Activity: In a study of 18 medicinal plants in New Caledonia evaluated in vitro against several parasites, Scaevola balansae and Premna serratifolia were the most active against Leishmania donovani.
• Immunomodulatory Activity: The roots of both plants of C. phlomidis and Premna integrifolia are incorporated in many valued Ayurvedic formulations. In a study evaluating the roots for immunomodulatory potential, both roots showed immunoprophylactic effect with C phlomidis showing higher response to specific immune activity. In no specific immune activity, both roots showed equal response.
• The effect of Premna integrifolia Linn. (Verbenaceae) on blood glucose in streptozotocin induced type 1 and type 2 diabetic rats.
• Hypoglycemic activity: In a study of 30 hypoglycemic plants from indigenous folk medicines, Preman integrifolia wsas one of 24 samples that showed significant blood glucose lowering activity.
• Premnazole / Anti-Inflammatory Activity: Premnazole, an isoxazole alkaloid from Premna integrifolia and Gmelina arborea exhibited signnificant anti-inflammatory activity in rats, comparable to that of phenylbutazone.
• Cardiac Stimulant Activity: PS contains alkaloids and iridoid glycoside. Study suggests that the ethanol extract produced a cardiotonic effect and the aqueous extract produced a ß-adrenergic effect.
• Hepatoprotective / Cytotoxic Activity: Study showed the alcoholic extract with significant hepatoprotective activity evidenced by decrease of serum enzymes, bilirubin and lipid peroxidation, comparable to drug silymarin. It also exhibited significant in-vitro cytotoxic activity. Results showed the alcoholic extract not only as an effective hepatoprotective agent, but with also significant antitumor activity.
• Antiparasitic Activity: In a study of 18 medicinal plants in New Caledonia evaluated in vitro against several parasites, Scaevola balansae and Premna serratifolia were the most active against Leishmania donovani.
KNOW ABOUT HERBS-VALLARAI
This medicinal plant is Centella grows along ditches and in low wet areas. Botanical name : Centela asiaticaFamily : Apiaceae Actions : antibacterial, anti-viral, anti-inflammatory, anti-ulcerogenic, anxiolytic, a cerebral tonic, a circulatory stimulant, a diuretic, nervine and vulnerary
. A decoction of juice from the leaves is said to relieve hypertension. .A poultice of the leaves is also used to treat open sores. Centella asiatica also has anti-oxidant properties. It works for venous insufficiency. It is widely used in Thailand for opium detoxification
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